Treatments Biologics Anti-IL-17 Ixekizumab Targets IL-17A Trials – UNCOVER-1, UNCOVER-2, UNCOVER-3 (Ixekizumab treatment for psoriasis , Br J Dermatol 2018; 178:674, DOI:10.1111/bjd.16050) Better than placebo or etanercept Good for fingernail psoriasis Rapid onset – starts to show some benefit in 1 week Approximate PASI improvement after 3 months: About 80% of patients will get at least ..

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