Blisters

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Congenital

– Epidermolysis Bullosa

Acquired

– Epidermolysis Bullosa Acquisita

– Pemphigoid

– Pemphigus

– Linear IgA

– Oedema blisters

– Infection – Bacterial / Viral

– Lichen planus pemphigoides

– Dermatitis herpetiformis

 

Workup

– FBC

– U+E

– LFT

– Immunoglobulins

– Glucose

– CRP

– Pemphigus / Pemphigoid serology

– TPMT level

– Swabs – Bacterial and Viral (including VZV and HSV 1 + 2)

– De-roof any large blisters (>20pence size)

– Dress with non-adherent dressing e.g. mepitel, jelonet, inadine

– 4mm biopsy x 2 – Lesional in formalin for histology, Perilesional in Michel’s transport media for IMF